This research aims to analyze the influence of STEM-based e-module teaching materials on students' scientific literacy skills. This research is experimental research with the concept of pretest-posttest non-equivalent control group design. The data collection method used in this research is the test and questionnaire method. The research was carried out in the odd semester of the 2023/2024 academic year. The population in this study were class VII students at Al-Islam Gunungpati Middle School, with research samples VII E for the experimental class and VII F for the control class. The technique used in sampling is purposive sampling technique. The research instrument is a pretest-posttest question sheet to measure scientific literacy skills and a questionnaire to measure scientific attitudes. The sampling technique used was a reated t-test, questionnaire data analysis, and N-gain. The research results showed that there was an effect of learning using e-module teaching materials during 3 meetings, namely 72.52% (good), 75.71% (good), 79.08% (good), and the results of the student questionnaire responses were 85.83 % (very good) so it can be concluded that STEM-based e-module teaching materials on global warming have an effect on students' scientific literacy skills.  
                        
                        
                        
                        
                            
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