Journal of Science and Technology: Alpha
Vol. 1 No. 2 (2025): Journal of Science and Technology: Alpha, April 2025

Penerapan Asam Lemak Hidroksamat dalam Industri Farmasi dan Kosmetik

Muhsinun, Muhsinun (Unknown)
Yanuar, Emsal (Unknown)



Article Info

Publish Date
30 Apr 2025

Abstract

This study aims to explore the application of hydroxamic fatty acids in the pharmaceutical and cosmetic industries, with a focus on their biological activities, product formulations, and compound stability in practical applications. Biological activity assays demonstrated that hydroxamic fatty acids exhibit significant antimicrobial effects against Escherichia coli and Staphylococcus aureus, as well as effective anti-inflammatory activity by reducing the production of pro-inflammatory cytokines in RAW 264.7 cells. Furthermore, anticancer tests on human breast cancer cells (MCF-7) showed that these compounds can inhibit cancer cell proliferation. In terms of product formulation, hydroxamic fatty acids were found to be stable in cosmetic products (facial serums and hair masks) and pharmaceutical products (topical ointments), with results indicating improvements in skin elasticity and hair quality, along with a reduction in inflammation symptoms in patients. However, a major challenge in the application of hydroxamic fatty acids lies in their complex synthesis process, which requires hazardous chemicals, thereby increasing production costs and impacting environmental sustainability. Therefore, further research is needed to develop more efficient and environmentally friendly synthesis methods. Overall, the findings of this study suggest that hydroxamic fatty acids hold significant potential for development as effective and safe active ingredients in the pharmaceutical and cosmetic industries.

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Journal Info

Abbrev

alpha

Publisher

Subject

Agriculture, Biological Sciences & Forestry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Languange, Linguistic, Communication & Media Social Sciences

Description

ALPHA: Journal of Science and Technology is a peer-review journal that could be access to the public, published by Lembaga Publikasi Ilmiah Nusantara with registered number ISSN 3089-4298. ALPHA provides a platform for researchers, academics, professionals, practitioners and students to embed and ...