MEDICA (International Medical Scientific Journal)
Vol. 6 No. 2 (2024): MEDICA (International Medical Scientific Journal)

The Relationship Between Hepatitis B Surface Antibody Levels and the Levels of Serum Glutamic Pyruvic Transaminase, Serum Glutamic Oxaloacetic Transaminase, and Total Bilirubin

Ni Putu Ditya Prabandari Dewi (Department of Medical Laboratory Technology, Politeknik Kesehatan Kementerian Kesehatan Denpasar, Denpasar, Bali, Indonesia)
Heri Setiyo Bekti (Department of Medical Laboratory Technology, Politeknik Kesehatan Kementerian Kesehatan Denpasar, Denpasar, Bali, Indonesia)
I Nyoman Purna (Department of Medical Laboratory Technology, Politeknik Kesehatan Kementerian Kesehatan Denpasar, Denpasar, Bali, Indonesia)



Article Info

Publish Date
31 May 2024

Abstract

Hepatitis B virus is a disease that can impair other functions of the liver. This study aims to determine the relationship between Hepatitis B antibody levels and the levels of SGOT (Serum Glutamic Oxaloacetic Transaminase), SGPT (Serum Glutamic Pyruvic Transaminase), and bilirubin. A quantitative analytic study with a cross-sectional approach was conducted. Data collection involved primary data in the form of hepatitis B serum samples and secondary data including SGOT levels, SGPT levels, bilirubin levels, age, gender, and medical history. The results showed a significant and inverse relationship between Hepatitis B antibody levels and SGOT levels, with a Sig. (2-tailed) value of 0.029 (<0.05) and a negative correlation coefficient of -0.627. Similarly, there was a significant and inverse relationship between Hepatitis B antibody levels and SGPT levels, with a Sig. (2-tailed) value of 0.003 (<0.05) and a negative correlation coefficient of -0.616. However, there was no significant relationship between Hepatitis B antibody levels and bilirubin levels, as indicated by a Sig. (2-tailed) value of 0.809 (>0.05), although the correlation was positive (correlation coefficient = 0.078). In conclusion, Hepatitis B antibody levels show a significant negative correlation with SGOT and SGPT levels, while the correlation with bilirubin levels is positive but not statistically significant.

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Journal Info

Abbrev

medica

Publisher

Subject

Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

Description

MEDICA (International Medical Scientific Journal), with registered number ISSN 2622-6596 (Print), 2622-660X (Online) is an Open Access and peer-reviewed journal presenting timely research on all aspects of health that other media have not published. Managed by the Borneo Scientific Publishing, ...