Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Vol 11 No 1 (2025): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan

EVALUASI KIMIA FISIKA DAN UJI STABILITAS SEDIAAN COLD CREAM YANG MENGANDUNG EKSTRAK ETANOL DAUN CIPLUKAN (Physalis angulata L.) DENGAN 3 JENIS MINYAK Olive, Caprylic Dan Parafin

Habibie Deswilyaz Ghiffari (Unknown)
Delladari Mayefis (Unknown)
Amelia, Ayu (Unknown)
Gina Fernanda (Unknown)



Article Info

Publish Date
28 May 2025

Abstract

Physalis angulata L. (ciplukan) is an annual plant with potential medicinal properties, including pain relief. This study aims to formulate a cold cream containing ciplukan leaf extract and evaluate its physical stability. The leaf extract was obtained by maceration using 96% ethanol and concentrated using a rotary evaporator. Cold cream formulations were prepared with extract concentrations of 0%, 5%, and 10%, utilizing three types of oils (olive, caprylic, and paraffin). Evaluations included organoleptic properties, pH, homogeneity, adhesion, spreadability, viscosity, cream type, and stability, analyzed using One-Way ANOVA. Results showed that all formulations exhibited good physical properties and were classified as oil-in-water (O/W) type creams. pH values ranged from 4 to 6, adhesion times from 1.19 to 4.94 seconds, and spreadability from 4.52 to 5.16 cm, with no significant differences among extract concentrations or oil types (p > 0.05). Increasing the extract concentration from 5% to 10% resulted in a slight decrease in pH, which remained within the safe range, maintained homogeneity, slightly reduced spreadability, and improved physical stability, especially at 10%. The formulation containing 10% ciplukan leaf extract showed the best stability and was well accepted as a cold cream preparation.

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Journal Info

Abbrev

jim

Publisher

Subject

Chemistry Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Description

Jurnal Ilmiah Manuntung is a journal on pharmaceutical and health sciences published by Sekolah Tinggi Ilmu Kesehatan Samarinda which includes the study of pharmaceutical sciences, medicine, synthetic organic chemistry, organic chemistry of natural materials, biochemistry, analytical chemistry, ...