Background: HIV/AIDS remains a significant public health issue globally, with adolescents being one of the most at-risk groups due to various risky behaviors. Limited access to comprehensive information contributes to the continued transmission of HIV within this age group. Objectives: This study aims to describe the level of knowledge about HIV/AIDS among adolescents in Indonesia. Methods: A systematic review was conducted by examining articles published between 2010 and 2024 that align with the study objectives. Ten relevant studies were identified and analyzed. Results: Among the studies reviewed, four reported that adolescent knowledge of HIV/AIDS was categorized as "good." Three studies indicated a "moderate" level of knowledge, and another three revealed a "poor" level. Conclusions: These findings highlight the ongoing need to enhance comprehensive HIV/AIDS education among Indonesian adolescents. Strategies should include school-based education programs, community outreach utilizing various accessible media, and integration of reproductive health education into the school curriculum.
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