journal of Basic Medical Veterinary
Vol. 14 No. 1 (2025): Journal of Basic Medical Veterinary, June 2025

Dayak Onion (Eleutherine palmifolia) Extract Reduces MSG-Induced Obesity in Mice

Rahmatullah, Aldin Akbar (Unknown)
Ratnaningtyas, Nurrohmah (Unknown)
Rahajeng, Anggreani Desi Ramadhani (Unknown)
Indrajaya, Putra (Unknown)
Firdaus, Ahmad Thoriqul (Unknown)
Hidayat, Rosid (Unknown)
Shaffirudin, Yosfiansya Fernandi (Unknown)
Zahli, Haikal Akmal (Unknown)
Irkhamy, Muhamad Naufal (Unknown)



Article Info

Publish Date
11 Jun 2025

Abstract

This study evaluated the anti-obesity effects of Dayak onion (Eleutherine palmifolia) extract in MSG-induced obese mice. Twenty-five male mice were divided into five groups: negative control (CMC-Na), positive control (MSG, 4 mg/g BW), and three groups receiving MSG plus Dayak onion extract at 30, 60, or 120 mg/kg BW for 52 days. Body weight was measured weekly, and abdominal fat (retroperitoneal, epididymal, peritoneal) was weighed using a digital scale on day 53. One-way ANOVA with Duncan’s post hoc test analyzed differences (p<0.05). MSG increased body weight (40.8 ± 1.1 g) and fat compared to the negative control (31.2 ± 0.5 g). Dayak onion extract dose-dependently reduced body weight (T1: 38.2 ± 0.6 g; T2: 36.0 ± 0.9 g; T3: 32.3 ± 0.6 g) and fat, with the 120 mg/kg dose nearing control levels. Flavonoids and anthraquinones in the extract likely drive these effects, suggesting Dayak onion’s potential as a natural anti-obesity agent. Human studies are needed to confirm these findings.

Copyrights © 2025






Journal Info

Abbrev

JBMV

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary

Description

This journal published original articles, review articles, and case studies in Indonesian or English, in the scope of JBMV has a broad coverage of relevant topics across veterinary basic medical sciences which includes: preclinical and paraclinical disciplines like Anatomy, Physiology, Biochemistry, ...