Background: Tooth extraction is a procedure that involves removing the tooth from the tooth socket. The wound healing process after tooth extraction ranges from 3 to 14 days. Wound healing can be treated with povidone iodine, but excessive use has side effects. Another alternative is red shoot leaves Methods: Experimental research with posttest only control group design. The sample was 30 male wistar rats, divided into 5 groups, namely positive control given povidone iodine, negative control base, 2% of Syzygium myrtifolium walp leaves extract, 4% of Syzygium myrtifolium walp leaves extract, and 6% of Syzygium myrtifolium walp leaves extract.. Results: Obtained a p value of 0.048 (p <0.05), indicating that there is a significant difference in the amount of epithelial thickness of all groups and the administration of Syzygium myrtifolium walp extract gel with a concentration of 6% on day 14 is thicker. Conclusion: Giving Syzygium myrtifolium walp leaves extract effect on wound healing after tooth extraction in male wistar rats.
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