International Journal of Applied Biology
Vol. 9 No. 1 (2025): International Journal of Applied Biology

Effect of Variation in Concentration of SCOBY Kombucha Gel Citrus Peel Extract (Citrus nobilis) on Wound Incision (Vulnus Scissum) in Mice (Mus musculus)

Shofiyya, Ainina Neihayatus (Unknown)
Eva Agustina (Unknown)
Funsu Andiarna (Unknown)
Irul Hidayati (Unknown)
Risa Purnamasari (Unknown)



Article Info

Publish Date
30 Jun 2025

Abstract

A laceration wound is damage to the skin tissue characterized by a neat outline of the wound edge, due to slices by sharp instruments or incisions during surgery. This study aims to evaluate the effect of variations in the concentration of SCOBY Kombucha gel preparations of orange peel extract (Citrus nobilis) on wound healing (Vulnus Scissum) in mice (Mus musculus). SCOBY Kombucha gel was made with six concentration variations (0%, 2%, 4%, 8%, 10%, and 12%) and tested for its effectiveness in accelerating wound healing. The research method involved making incision wounds on male mice, followed by applying the gel according to the specified concentrations. The results showed that SCOBY Kombucha gel with a concentration of 12% was most effective in accelerating wound healing, approaching the effectiveness of the positive control (bioplacenton). Analysis showed that the increase in gel concentration was directly proportional to the effectiveness of wound healing, where higher concentration gels showed significantly faster wound closure.

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Journal Info

Abbrev

ijoab

Publisher

Subject

Agriculture, Biological Sciences & Forestry Automotive Engineering Energy Environmental Science

Description

International Journal of Applied Biology is an international, peer reviewed journal, publishing high-quality research. International Journal of Applied Biology only publishes manuscripts in English. Please see the journal's Focus & Scope for information about its Scope and peer-review policy. ...