<![CDATA[Background: Tuberculosis (TB) control and prevention in children is a global health priority. Despite various preventive efforts undertaken by the South Purwokerto Community Health Center, the incidence of childhood TB continues to rise. Purpose: This study aimed to determine the behaviors of toddlers' mothers in preventing TB in children in Teluk Subdistrict, South Purwokerto. Methods: This study employed an analytical observational design with a cross-sectional approach. The population comprised 522 mothers of toddlers in Teluk Subdistrict, with a sample of 81 respondents selected through a multi-stage sampling procedure involving cluster and purposive sampling from integrated healthcare centers in several community units. Primary data were collected using a questionnaire in November 2023. Data analysis involved chi-square tests and multiple logistic regression. Results: The findings revealed a significant association between mothers' attitudes (p-value = 0.02) and healthcare workers' support (p-value = 0.003) and their behaviors in preventing childhood TB. Conversely, variables such as education level (p-value = 0.78), occupation (p-value = 0.51), knowledge (p-value = 0.90), and information access (p-value = 0.10) showed no significant relationship. Logistic regression analysis indicated that healthcare workers' support was the most influential factor in determining mothers' behaviors in preventing childhood TB (p-value = 0.02) (OR = 3.53). Conclusion: Healthcare workers' support emerged as the primary determinant of mothers' behaviors in preventing childhood TB in Teluk Subdistrict, South Purwokerto.]]>
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