This study aims to explore the role of midwife and family support in the utilization of the Maternal and Child Health Handbook by pregnant women. Study used a quantitative cross-sectional design. The study site was the Kalianda Community Health Center, South Lampung, and included all pregnant women in their first to third trimesters registered with the KIA register. A purposive sampling method was used to select 120 pregnant women, involving 20 midwives as additional data sources. The research instrument, a structured questionnaire, was tested for validity and reliability, showing good results (validity coefficient r = 0.74–0.82; Cronbach's Alpha = 0.85). Data were collected through direct interviews by trained enumerators and analyzed using univariate and bivariate analysis techniques, including the Chi-square test. The results show the majority of respondents were aged 20–35 and had a relatively high level of education, which positively impacted their ability to understand health information. Good midwife support was significantly associated with the utilization of the KIA Handbook, with 83.3% of respondents who received good support successfully using the handbook. Family support also showed a positive influence, with 76.4% of respondents who received good support being able to use the KIA Handbook efficiently.
                        
                        
                        
                        
                            
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