Jurnal Ilmiah Medicamento
Vol 11 No 2 (2025): Jurnal Ilmiah Medicamento (In progress)

Skincare Antijerawat: Formulasi Masker Gel Peel-Off Etil P-Metoksisinamat dari Kaempferia galanga L dengan Polivinill Alkohol sebagai Gelling Agent

Kusuma, Ika Maruya (Unknown)
Indrawati, Teti (Unknown)
Zulfah, Zulfah (Unknown)



Article Info

Publish Date
30 Sep 2025

Abstract

Herbal medicines are increasingly used as antibacterial therapy due to their accessibility and affordability. Kaempferia galanga L. (kencur) rhizome contains ethyl p-methoxycinnamate (EPMS), an active compound with anti-acne properties. EPMS at 1.2% in cream formulations has shown antibacterial activity against Propionibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus. However, creams are unsuitable for oily skin as they may worsen acne. Peel-off gels offer a better alternative because it is non-greasy, supports exfoliation, stimulates cell regeneration, minimizes pores, and helps cleanse and moisturize the skin. This study aimed to formulate a physically stable anti-acne peel-off gel containing EPMS using polyvinyl alcohol (PVA) at 10% and 12%. EPMS was isolated from kencur rhizome and incorporated into gel bases. Evaluations included organoleptic properties, viscosity, homogeneity, pH, drying time, spreadability, and accelerated stability at 27 ± 2 °C and 40 ± 2 °C for 21 days. Results showed that EPMS can be successfully formulated into peel-off gels with PVA 10% and 12%. The gels exhibited yellowish-white color, honey-like odor, homogeneity, pH 5.21–5.35, drying time 17–30 minutes, spreadability 55–68 mm, and viscosity 4,900–16,000 cPs. All formulations maintained physical stability under test conditions. This study provides a scientific basis for the development of natural-based cosmetic products that are safe, particularly for oily skin, and do not worsen acne conditions.

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Journal Info

Abbrev

Medicamento

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

Jurnal Ilmiah Medicamento (JINTO) dengan nomor registrasi e-ISSN 2356-4814 didirikan pada tahun 2014, dan publikasi online dimulai pada tahun 2015. Jurnal diterbitkan dalam bahasa Indonesia. Awalnya JINTO diterbitkan oleh Akademi Farmasi Saraswati Denpasar. Namun sejak awal tahun 2019, penerbit ...