Pulmonary tuberculosis (TB) is an infectious disease that remains a public health problem in Indonesia, including in the work area of the Oesapa Community Health Center in Kupang City. TB transmission occurs through droplets expelled when an infected person coughs or sneezes. This study aims to determine the relationship between knowledge and behaviors for preventing pulmonary TB transmission in TB patients. This study used a quantitative approach with a cross-sectional design. The population in this study was all adult pulmonary TB patients registered at the Oesapa Community Health Center in 2024, with a sample size of 70 individuals selected using a total sampling technique. The independent variables in this study included knowledge and attitudes, while the dependent variable was behavior related to preventing pulmonary TB transmission. Data were collected using a closed-ended questionnaire and analyzed univariately and bivariately using the chi-square test. The results showed that the majority of respondents (66.7%) exhibited poor prevention behavior. Furthermore, there was a significant relationship between knowledge (p=0.004) and attitude (p=0.004) and behavior related to preventing pulmonary TB transmission. The study concluded that prevention behavior is influenced by predisposing factors (knowledge and attitude), and aligns with Lawrence Green's theory. These results are expected to provide input for Community Health Centers (Puskesmas) in designing health promotion strategies and educational interventions to reduce the risk of TB transmission in the community.
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