Jurnal Farmasi
Vol. 12 No. 2 (2023): Jurnal Farmasi (Journal of Pharmacy), October 2023

UJI AKTIVITAS ANTIPIRETIK EKSTRAK ETANOL BAWANG LANANG HITAM (ALLIUM SATIVUM L.) PADA TIKUS PUTIH JANTAN DENGAN METODE PERKOLASI

Pramesti Listya Agatha, Cindy (Unknown)
Wisnu Kusuma, Eka (Unknown)
Ingrid Anggaraini, Devina (Unknown)



Article Info

Publish Date
15 Oct 2023

Abstract

Black Onion (Allium Sativum L.) is a species of garlic that is fermented and widely used in food or health. This study aims to determine the black male onion extract antipyretic effectiveness along with to determine the impact of ethanol extract black male onion at dossage of 50mg/KgBb, 100mg/KgBb, 200mg/kgbb on male white rats induced brewer's yeast.. In this study, 25 male white rats were given five treatments: a negative control (CMC-Na), a positive control (Paracetamol 45mg/KgBb), and black onion extract treatment groups with dosages of 50mg/KgBb, 100mg/KgBb, and 200mg/KgBb. Brewer's yeast was administered intraperitoneally. Body temperature is measured rectally with a digital thermometer every 30 minutes for 150 minutes. The data obtained were used to calculate AUC, and the mean data of AUC was analyzed by saphiro wilk test and one-way ANOVA test. Body temperature measurements revealed that an ethanol extract of black onion had the most potent antipyretic effect at a dosage of 100 mg/KgBb

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Journal Info

Abbrev

jf

Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Description

JURNAL FARMASI (Journal Of Pharmacy) adalah jurnal ilmiah resmi yang dikeluarkan oleh Sekolah Tinggi Ilmu Kesehatan Nasional dengan nomor p-ISSN 2302-7436 e-ISSN 2656-8950. JURNAL FARMASI (Journal Of Pharmacy) berisikan jurnal-jurnal ilmiah dalam semua aspek ilmu pengetahuan dan teknologi di bidang ...