Indonesian Journal of Pharmaceutical Science and Technology
Vol 12, No 3 (2025)

Formulation and Antibacterial Activity of Basil (Ocimum basilicum Linn.) Essential Oil Emulgel

Nilmawati, Nilmawati (Unknown)
Novitasari, Putri Rachma (Unknown)
Nuraisyah, Fatma (Unknown)
Rusdi, Niswa Fadilah (Unknown)
Widiyastuti, Lina (Unknown)



Article Info

Publish Date
31 Oct 2025

Abstract

Basil (Ocimum basilicum Linn.) essential oil contains methyl chavicol, which exhibits antibacterial properties. Basil essential oil has volatile and hydrophobic properties, so it is necessary to have an emulgel preparation that can stabilize and enhance its topical activity. This study aims to formulate an emulgel of basil essential oil and investigate its antibacterial activity against Staphylococcus aureus. Basil essential oil was analyzed using the GC-MS. The formulas of Basil essential oil emulgel were created through concentration variations of 5%, 7.5%, and 10%, respectively. These formulas were then tested for organoleptic properties, viscosity, pH, spreadability, and adhesion time. Additionally, antibacterial activity tests were conducted using the well diffusion method. Basil essential oil analysis identified methyl chavicol at 81.34%. All formulas had the white semi-solid form and they had specific basil odours, viscosity 1013.83 ±714.29; 1644.68 ± 888.68; 1923.26 ± 1733.67 cps, pH 5.73; 6.02; 6.90, spreadability 19.61 ± 0.24; 18.28 ± 0.32; 17.57 ± 0.26 gram.cm/second and adhesion time 8.03 ± 1.85; 5.07 ± 0.43; 5.51 ± 0.14 second. Furthermore, all the formulas inhibited the growth of Staphylococcus aureus (p<0.05). The 7.5% basil essential oil emulgel’s formula provides optimal results in terms of physical stability and antibacterial activity.

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Journal Info

Abbrev

ijpst

Publisher

Subject

Computer Science & IT Medicine & Pharmacology

Description

Jurnal Sains dan Teknologi Farmasi Indonesia (IJPST) adalah publikasi ilmiah pada seluruh aspek Sains dan Teknologi Farmasi. Jurnal ini diterbitkan 3 kali setahun untuk menyediakan forum bagi apoteker, dan profesional kesehatan lainnya untuk berbagi praktik terbaik, meningkatkan jaringan kerja dan ...