Life Science and Biotechnology
Vol. 3 No. 1 (2025): May 2025

Chemical Profiling of Locally Grown Zingiber officinale Roscoe (Ginger) Rhizomes using GC-MS and Biological Activities

Farhan, Abdillah Maulana (Unknown)
Ilmiah , Ika iffah (Unknown)
Mufidi, Farah Fakhirah (Unknown)
Perkasa, Excel Taruna Reksa (Unknown)
Shodiq, Muhammad Husein (Unknown)
Shodiq, Abdulloh Hasan (Unknown)



Article Info

Publish Date
29 Oct 2025

Abstract

Ginger (Zingiber officinale Roscoe), a widely used rhizomatous species of the family Zingiberaceae, possesses extensive medicinal value owing to its diverse phytochemical composition. This study aimed to characterize the bioactive constituents of locally grown ginger rhizomes using Gas Chromatography–Mass Spectrometry (GC–MS) to elucidate their potential pharmacological activities. GC–MS analysis enabled the detection of volatile and semi-volatile compounds based on retention time and molecular ion fragmentation patterns, providing a comprehensive chemical profile of the extract. A total of 39 compounds were identified, of which 14 exhibited relative abundances exceeding 3%. Major constituents included sesquiterpenes and phenolic derivatives known for their antioxidant, antimicrobial, anti-inflammatory, and anticancer properties. The presence of these bioactive metabolites confirms the therapeutic potential of Z. officinale as a natural source of bioactive agents and supports its continued exploration for pharmaceutical and nutraceutical applications

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Journal Info

Abbrev

LSB

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

Description

Life Science and Biotechnology publishing rigorously peer-reviewed research that seeks to advance our understanding of fundamental processes in biology. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to ...