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Marchantia polymorpha : Studi Profil dan Kandungan Senyawa Bioaktif Potensial sebagai Obat di Masa Mendatang Farhan, Abdillah Maulana; Masayu, Muhammad Zulfikar Arian; Azizah, Alya Najwa; Risqi, Alexandria Zazila; Shodiq, Abdulloh Hasan; Shodiq, Muhammad Husein
Jurnal Penelitian Sains Vol 27, No 2 (2025)
Publisher : Faculty of Mathtmatics and Natural Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56064/jps.v27i2.1101

Abstract

Marchantia polymorpha is one type of liverwort thallus. This liverwort has three subspecies: M. polymorpha subsp. polymorpha, M. polymorpha subsp. ruderalis, and M. polymorpha subsp. montivagans. These three subspecies exhibit different morphologies and have their own characteristics. M. polymorpha subsp. polymorpha is characterized by a thick black line running down the center of the thallus to the tip, while M. polymorpha subsp. ruderalis has a broken central line on the thallus, and M. polymorpha subsp. montivagans has no central line on its thallus. M. polymorpha contains bioactive compounds that have potential medicinal properties. Analysis using GC-MS indicates that there are 10 dominant compounds in this liverwort, with 8 of them being potentially beneficial for health, acting as antimicrobials, anticancer agents, anti-inflammatory agents, and having other biological activities. The aim of this study is to explore further information regarding the profile and bioactive compound content of M. polymorpha using a literature or secondary data approach. The benefits of this study are to advance the stages of primary research and to provide an overview of the morphology, distribution, life cycle of the liverwort, the content of its compounds, and its potential as a medicine in the future. 
Chemical Profiling of Locally Grown Zingiber officinale Roscoe (Ginger) Rhizomes using GC-MS and Biological Activities Farhan, Abdillah Maulana; Ilmiah , Ika iffah; Mufidi, Farah Fakhirah; Perkasa, Excel Taruna Reksa; Shodiq, Muhammad Husein; Shodiq, Abdulloh Hasan
Life Science and Biotechnology Vol. 3 No. 1 (2025): May 2025
Publisher : Department of Biology, Faculty Mahematics and Natural Sciences, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Ginger (Zingiber officinale Roscoe), a widely used rhizomatous species of the family Zingiberaceae, possesses extensive medicinal value owing to its diverse phytochemical composition. This study aimed to characterize the bioactive constituents of locally grown ginger rhizomes using Gas Chromatography–Mass Spectrometry (GC–MS) to elucidate their potential pharmacological activities. GC–MS analysis enabled the detection of volatile and semi-volatile compounds based on retention time and molecular ion fragmentation patterns, providing a comprehensive chemical profile of the extract. A total of 39 compounds were identified, of which 14 exhibited relative abundances exceeding 3%. Major constituents included sesquiterpenes and phenolic derivatives known for their antioxidant, antimicrobial, anti-inflammatory, and anticancer properties. The presence of these bioactive metabolites confirms the therapeutic potential of Z. officinale as a natural source of bioactive agents and supports its continued exploration for pharmaceutical and nutraceutical applications