Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Vol. 5 No. 1 (2025): Jurnal Ilmu Kedokteran dan Kesehatan Indonesia

Hubungan HDL, LDL, Apo A, dan Apo B dengan Kejadian Penyakit Jantung Koroner

Ruslim, Welly Hartono (Unknown)
Firmansyah, Yohanes (Unknown)
Santoso, Alexander Halim (Unknown)
Edwin Destra (Unknown)
Gunaidi, Farell Christian (Unknown)
Fajarivaldi, Kresna Bambang (Unknown)



Article Info

Publish Date
17 May 2025

Abstract

Coronary heart disease (CHD) in the elderly represents the primary clinical manifestation of atherosclerosis and remains a leading cause of death and morbidity. This cross-sectional study aimed to evaluate the role of High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), Apolipoprotein-A (APO-A), and Apolipoprotein-B (APO-B) in the diagnosis and prevention of CHD among the elderly population. The results demonstrated that both APO-A and HDL were significantly negatively correlated with CHD (r = -0.336, p = 0.008; r = -0.274, p = 0.032), suggesting that higher levels of APO-A and HDL are associated with a lower risk of CHD. Conversely, APO-B and LDL showed a significant positive correlation with CHD (r = 0.411, p = 0.001; r = 0.358, p = 0.005), indicating that elevated levels of APO-B and LDL are linked to an increased risk of CHD. These findings highlight that measuring Apolipoprotein A and B levels may offer more valuable insights into atherosclerotic and cardiovascular risk assessment and may enhance the effectiveness of CHD prevention compared to traditional lipid profiles.

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Journal Info

Abbrev

jikki

Publisher

Subject

Health Professions Public Health

Description

Jurnal Ilmu Kedokteran dan Kesehatan Indonesia (JIKKI), ISSN: 2827-797X online dan ISSN:2827-8488 cetak. Jurnal JIKKI diterbitkan Amik Veteran Porwokerto, terbit setahun Tiga kali (Maret, Juli dan November) menerapkan proses peer-review dalam memilih artikel berkualitas berdasarkan penelitian ilmiah ...