Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Vol. 5 No. 2 (2025): Juli: Jurnal Ilmu Kedokteran dan Kesehatan Indonesia

Uji Aktivitas Antioksidan Ekstrak Etanol Herba Sirih Cina (Peperomia pellucida L.) dengan Metode DPPH

Jecika Stefany Br Tumanggor (Unknown)
Razoki Razoki (Unknown)
Muhammad Yunus (Unknown)
Daimah Wirdatus Sanaun Harahap (Unknown)



Article Info

Publish Date
02 Jun 2025

Abstract

Free radicals are reactive compounds that can cause damage to cells, enzymes, lipids, and even DNA, thus triggering various degenerative diseases. Antioxidants neutralize free radicals and prevent oxidative damage. Chinese betel herb (Peperomia pellucida L.) is known to contain phenol and flavonoid secondary metabolite compounds that act as natural antioxidants. This study aims to test the antioxidant activity of ethanol extract of Chinese betel herb with DPPH (2,2-diphenyl-1-picrylhydrazyl) method. Extraction was done by maceration method using 80% ethanol solvent. Antioxidant activity was tested by reacting the extract against DPPH solution and measuring the absorbance using UV-Vis spectrophotometry. The results showed an IC₅₀ value of 32.97 ppm, which is classified as very strong antioxidant activity. These results indicate that ethanol extract of Chinese betel herb has great potential as a source of natural antioxidants.  

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Journal Info

Abbrev

jikki

Publisher

Subject

Health Professions Public Health

Description

Jurnal Ilmu Kedokteran dan Kesehatan Indonesia (JIKKI), ISSN: 2827-797X online dan ISSN:2827-8488 cetak. Jurnal JIKKI diterbitkan Amik Veteran Porwokerto, terbit setahun Tiga kali (Maret, Juli dan November) menerapkan proses peer-review dalam memilih artikel berkualitas berdasarkan penelitian ilmiah ...