<![CDATA[Women frequently suffer from menstrual abnormalities, such as dysmenorrhea, which primarily affects teenagers. Teenagers who experience dysmenorrhea at school may engage in less educational activities. Adolescent dysmenorrhea self-medication behaviour will be impacted by ignorance. The study objective was to determine the knowledge of self-medication for dysmenorrhea before and after education, and to determine the effect of education on knowledge of self-medication for dysmenorrhea. This study is a quantitative study with a quasi-experimental design method of non-equivalent control group. Sampling with proportion sampling with inclusion and exclusion criteria with a sample size of 82 respondents. The data analysis used the Wilcoxon and Mann-Whitney tests. The average pre-test value was 30.5% (good category), and the post-test was 65.9% (good category). The results of the Wilcoxon test obtained the Asymp. Sig (2-tailed) value in the treatment group 0.000 <0.05, stating that there was a difference in the level of knowledge before and after education was given. The Asymp. Sig (2-tailed) value in the control group obtained a value of 0.235> 0.05, so it was stated that there was no difference in knowledge in the pre-test and post-test. The results of the Mann-Whitney test showed that there was an effect of education on knowledge before and after education with an Asymp. Sig (2-tailed) value of 0.000 <0.05. Providing education with the lecture method and interactive discussion using video media related to self-medication for dysmenorrhea provided an increase in knowledge medication for dysmenorrhea in female students of Vocational High School Muhammadiyah 03 Metro with a p-value of 0.000 <0.05. related to self-medication for dysmenorrhea. There was an effect of providing education on knowledge of self-medication for dysmenorrhea in female students of Muhammadiyah 03 Metro Vocational School with a p-value of 0.000<0.05.]]>
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