Background: Sexually Transmitted Infections (STIs) remain a serious health problem, especially among at-risk populations such as Female Sex Workers (FSWs) and Ladies Companions (LCs). Consistent condom use has been proven effective in preventing STIs, however compliance is still low. Objective: This study aims to analyze the relationship between condom use and symptoms of STIs and HIV/AIDS among at-risk populations in Semarang City. Method: This is an observational analytic cross-sectional study. Study sample consisted of 20 sexually active LC/FSW respondents with symptoms of STIs or HIV/AIDS. Data were collected through interview questionnaires. Analysis was performed using the Chi-Square test and Fisher's exact test. Results: 65% of respondents did not use condoms consistently, and 70% experienced symptoms of STIs. There was a significant relationship between condom use and STI symptoms (p < 0.05). Conclusion: Inconsistent condom use is associated with increased symptoms of STIs. Increased education and improved access to contraceptives are essential for at-risk populations.
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