Indonesian Journal of Engineering and Technological Innovation
Vol. 1 No. 1 (2025): March: Indonesian Journal of Engineering and Technological Innovation

Curcumin's Potential as a Therapeutic Agent for Hpv-Induced Cancer

Triani Nur Fitri (Unknown)
Adilla Syahsiyatun Najah (Unknown)
Syifa Salsabila Mulyani (Unknown)
Wulan Pertiwi (Unknown)

Article Info

Publish Date
31 Mar 2025

Abstract

Curcumin, the main active compound of turmeric (Curcuma longa), shows potential as a therapeutic agent for Human Papillomavirus (HPV)-induced cancer. This study examines the mechanism of action of curcumin in inhibiting the proliferation of HPV-infected cervical cancer cells, including its anti-inflammatory, anti-cancer, and anti-viral properties reviewed from several references. Curcumin works by suppressing the expression of E6 and E7 oncoproteins, induction of apoptosis, and modulation of signaling pathways that support tumor growth, such as NF-κB. Although curcumin has great potential, the challenges of low bioavailability and rapid metabolism in the body still need to be overcome. Further research is needed to optimize the formulation and delivery method of curcumin as a cancer therapy.

Copyrights © 2025




Citation Download
RIS
EndNote, Reference Manager, ProCite
BibTex
Latex, Jabref
Original Source
Download Original
Google Scholar
Check in Google Scholar
Journal Info
Indonesian Journal of Engineering and Technological Innovation
Website

Abbrev

ijeti

Publisher

Yayasan Cendekia Gagayunan Indonesia

Subject

Aerospace Engineering Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Electrical & Electronics Engineering Engineering Industrial & Manufacturing Engineering Mechanical Engineering Transportation

Description

Indonesian Journal of Engineering and Technological Innovation (IJETI) is a peer-reviewed, open-access scientific journal that publishes original research articles, review papers, and short communications in the field of engineering and technology. The journal aims to serve as a platform for ...