Jurnal Kedokteran Methodist
Vol. 15 No. 2 (2022): Jurnal Kedokteran Methodist

Hubungan gambaran CT-Scan paru dengan kadar monosit dan laju endap darah pada pasien SARS-COV-2.

Novianti, Wulan (Unknown)
Anto, Endy Juli (Unknown)
B. Hutagalung , Sanggam (Unknown)



Article Info

Publish Date
30 Dec 2022

Abstract

Background : Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of Coronavirus that is transmitted to humans that attacks the respiratory system and manifests as inflammation of the lung parenchyma. CT Scan can be used as an alternative diagnostic measure to find out the radiological picture of COVID19 patients. monocytes/macrophages can serve as reservoirs which, consequently, will serve as vectors of virus spread to other tissues, but this has not been proven in SARS-CoV-2. Inflammation is an important body mechanism to protect itself from foreign objects. During this process, cells release various proinflammatory cytotoxins, including active-phase proteins such as CRP (C-Reactive Protein) and fibrinogen. Then, the increase in fibrinogen levels further becomes a factor that increases the ESR. Research Objectives: To determine whether there is a relationship between CTScan Lung images and Monocyte Levels and ESR in SARS-CoV-2 patients. Research Methods: The type of research carried out is observational analytic measurement, with a cross sectional design the researcher makes observations or measurements of variables at certain times. Research results: the frequency distribution on CT-SCAN images of the lungs of SARS-CoV-2 patients was found to be the most GGO with a frequency of 22 people (38.6%) and the frequency distribution of monocyte and ESR levels in SARS-CoV2 patients obtained the highest levels of monocytes. in patients with SARS-CoV-2 is normal with a frequency of 35 people (61.4%) and the ESR level is normal with a frequency of 44 people (77.2%). In the analysis, there was a significant relationship between pulmonary CT-SCAN images on monocyte levels and ESR in patients with SARS-CoV-2 p-values = 0.022 and 0.003, and had a simultaneous and partial effect. Conclusion: there is a relationship between CT-SCAN images of the lungs of SARSCoV-2 patients and the levels of monocytes and ESR in the body.

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Journal Info

Abbrev

jkm

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary Other

Description

Jurnal Kedokteran Methodist (JKM) is a peer-reviewed, open-access journal that welcomes manuscripts in basic and clinical research, encompassing all aspects of medicine, health sciences, and pharmacy. Reports on genomics, epigenetics, and stem cells are welcome as well. The journal covers original ...