<![CDATA[The transformation of learning in higher education is an urgent need to face global challenges and realize the vision of Golden Indonesia 2045. This article aims to examine and formulate the development of a higher education curriculum based on the Ulul Ilmi Model that integrates Islamic values with 21st-century skills. The Ulul Ilmi Model is understood as a learning paradigm that emphasizes the unity between spiritual depth, intellectual breadth, and analytical acumen in the educational process. The research method used is a systematic literature study with a qualitative-analytical approach to relevant primary and secondary sources, including studies of the Qur'an, Islamic educational thought, national education policies, and literature on 21st-century skills. The results of the study indicate that the integration of Islamic values such as monotheism, morality, scientific ethos, and social responsibility with 21st-century skills including critical thinking, creativity, collaboration, communication, and digital literacy can shape the profile of graduates who are intellectually superior, have character, and are adaptive to changing times. The implementation of the Ulul Ilmi Model in curriculum development encourages holistic, contextual learning, and is oriented towards strengthening character and global competence. This article is expected to provide a conceptual contribution to the development of a higher education curriculum that is based on Islamic values and is responsive to the demands of the nation's future towards Golden Indonesia 2045]]>
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