Indonesian Journal of Cancer
Vol 19, No 4 (2025): December

Adrenocortical Carcinoma with Infiltrated and Ruptured Inferior Vena Cava in Adult Woman

Maligan, Deden Jinar Wahyudi (Unknown)
Maulana, Akhada (Unknown)
Danurdoro, Aria (Unknown)
Santosa, Hilda (Unknown)
Kumaladewi, Baiq Ratna (Unknown)



Article Info

Publish Date
30 Dec 2025

Abstract

Introduction: Adrenocortical carcinoma (ACC) is a malignant tumor that develops in the adrenal cortex. This case involves a rare, aggressive disease that demands specialized knowledge and optimal treatment for a favorable prognosis. This study aims to present the case of a woman with a right-sided ACC extending into the inferior vena cava (IVC), managed through radical resection and IVC repair.Case Presentation: A 50-year-old female presented with a complaint of a lump in the upper right abdomen, which she noticed three months ago. Abdominal computed tomography (CT) scan with contrast revealed a solid, inhomogeneous mass in the right suprarenal region measuring 12 cm x 11 cm. However, three days before the scheduled operation, the patient was brought to the emergency department with complaints of weakness and muscle weakness throughout the body. During the surgery, an adrenalectomy on the right side revealed a tumor infiltrating the IVC, causing venous rupture. The histological examination of the right adrenal tissue revealed ACC, infiltration of tumor cells beyond the capsule, lymphovascular infiltration, and no evidence of tumor cell infiltration into the kidney tissue. The treatment approach for this ACC case involved a complete surgical resection with open adrenalectomy and vena reconstruction. Postoperative results indicated improved patient condition, including symptom relief and favorable biochemical evaluation after surgery.Conclusion: Our patient had a right-sided ACC with local vascular infiltration into the IVC.

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Journal Info

Abbrev

ijoc

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

Description

Indonesian Journal of Cancer is a peer-reviewed and open-access journal. This journal is published quarterly (in March, June, September, and December) by Dharmais Cancer Hospital - National Cancer Center. Submissions are reviewed under a broad scope of topics relevant to experimental and clinical ...