Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical)
Vol. 8 No. 2 (2025): OKTOBER 2025

Formulation And Evaluation Of Lip Balm Preparation From Watermelon Seed Extract (Citrullus lanatus) As Lip Moisturizer

Alter Y. Runtu (Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Christian University of Indonesia in Tomohon)
Soniya Tumuju (Program Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon)
Douglas N. Pareta (Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Christian University of Indonesia in Tomohon)
Andry Natanel (Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Christian University of Indonesia in Tomohon)
Anggelina A. Pangalila (Program Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon)
Adolfina Sumagando (Department of Biology, Faculty of Mathematics and Natural Sciences, Christian University of Indonesia in Tomohon)
Marshella M. Mokoagouw (Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Christian University of Indonesia in Tomohon)



Article Info

Publish Date
30 Oct 2025

Abstract

This study aimed to formulate and evaluate a lip balm preparation containing watermelon seed extract (Citrullus lanatus) as a safe and effective natural lip moisturizer, in response to the increasing demand for plant-based cosmetic products. The extract was obtained using the maceration method, and four lip balm formulations were prepared with extract concentrations of 0%, 3%, 6%, and 9%. The preparations were evaluated through physical characterization tests, irritation assessment, hedonic evaluation, and stability testing over a 10-week storage period. The results indicated that all formulations were stable, exhibited acceptable pH values and melting points, and did not cause irritation. Increasing extract concentration significantly improved spreadability and moisturizing performance, with the 9% formulation receiving the highest preference among panelists. These findings suggest that watermelon seed extract has strong potential as a natural and safe active ingredient for lip care formulations.

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Journal Info

Abbrev

jbt

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

Description

Jurnal Biofarmasetikal Tropis (The Tropical Journal of Biopharmaceutical) is an Nasional journal presenting original research in Pharmacology and Toxicology, Pharmaceutical Chemistry, Drug Discovery, Pharmacokinetics, Pharmaceutical Biology, Herbal Medicines, Pharmaceutics, Pharmaceutical ...