This study aims to analyze the validity of the developed E-LKPD. The method used is (R&D) with a 4D development model. The sample in this study were 34 students of class X of SMA Negeri 12 Semarang and the sampling technique used was purposive sampling . The data collection instrument was a validation questionnaire assessed by expert validators of media, materials, learning methodology, scientific argumentation, teacher and student assessments. The percentage of validation results from media experts was 87.5%, material experts were 97.2%, learning methodology experts were 87.5%, scientific argumentation skills experts were 90.6%, and biology teacher assessments were 98%. The student readability test showed a percentage of 88%. Based on the results of the overall data analysis, it was concluded that the E-LKPD based on the RADEC model integrated with SSI to train scientific argumentation skills was declared valid and good for use in Biology learning.
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