Folia Medica Indonesiana
Vol. 52 No. 2 (2016): APRIL - JUNE 2016

AMPICILLIN SULBACTAM AND CEFOTAXIME ARE SIMILARLY EFFECTIVE IN PEDIATRIC PNEUMONIA

Puspitasari, Diny (Unknown)
Hasmono, Didik (Unknown)
Rahman, Taufiqur (Unknown)



Article Info

Publish Date
08 Jun 2016

Abstract

Pneumonia is an infection of the lungs that occurs and still cause high mortality in young children today. The main cause is bacterial or viral. Antibiotics still recommended though it is difficult to know the cause is bacterial or viral. Ampicillin be the first option some guideline. Increased resistance worldwide become one of them concerns the effectiveness of antibiotics. The main treatment of toddler pneumonia in Muhammadiyah Hospital Lamongan are ampicillin sulbactam and cefotaxime. The study was conducted to analyze the effectiveness of both antibiotics. This study aims to analyze comparison in the use of ampicillin sulbactam and cefotaxime pneumonia patients aged 3-59 months from November 2013 to March 2014. Patients who met the inclusion criteria were prospectively observed for clinical data, laboratory data, the data microbiology. After it is analyzed to know the difference between the effectiveness of antibiotics. In this study of 29 patients included in the inclusion criteria, 17 patients who received antibiotics ampicillin sulbactam and 12 patients receiving cefotaxime. In the comparison of the mean pulse pulse is known there is a significant reduction in both groups of patients on the second day and was not significantly different between the two groups (p = 0.084). Likewise, the average ratio of temperature (p = 0.117), breath rate (p = 0.839), leukocytes of patients (p = 0.429). Length of stay for ampicillin sulbactam group was 4.77 days and 5.17 days for cefotaxime group. Analysis showed no differences between the two groups for lenght (p = 0.275). Of the 22 patients who were sampled for blood culture examination only 1 patient with positive results. Based on these results we can conclude that ampicillin sulbactam and cefotaxime effective in cases of children pneumonia, and there is no distinction based on the parameters in body temperature, breath rate, pulse, leukocytes and long hospitalization of patients. Regimentation dosage is appropriate based on guidelines, and length of stay less than 10 days. Found no side effects of both drugs.

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Journal Info

Abbrev

FMI

Publisher

Subject

Other

Description

Folia Medica Indonesiana publishes articles in the field of medical science in particular and health sciences in general, as well as a variety of other fields related to those two disciplines. Most of the articles are research article, and others are articles on case reports and literature review. ...