<![CDATA[Introduction: Central venous oxygen saturation (ScvO₂) is generally more preferred over mixed venous oxygen saturation (SvO₂) for indirectly assessing tissue oxygenation due to its simplicity, cost-effectiveness, and routine use during cardiac surgery. Precise tissue oxygenation monitoring during cardiac surgery is crucial for optimizing patient management and improving perioperative outcomes. Objective: This literature review evaluates the role of ScvO₂ in managing and predicting outcomes in cardiac surgery patients. Review: From 93 identified articles, 38 studies met the inclusion criteria. These studies explored ScvO₂ as a postoperative outcome predictor and a perioperative therapeutic guide. These studies also explored its correlation with other parameters and its normal value ranges. Their findings indicate that using ScvO₂ as a guide for blood transfusion does not significantly alter postoperative outcomes compared to standard practices. Continuous ScvO₂ monitoring can also predict fluid responsiveness in critically ill patients. The value of ScvO₂ is less consistent in predicting poor postoperative outcomes and should therefore be combined with lactate level monitoring. When interpreting ScvO₂ values as a substitute for SvO₂, one must consider the variability between the two, especially in cases of severe hypoperfusion. Furthermore, although the recommended target for ScvO₂ is above 70%, an upper limit should also be established because ScvO₂ values exceeding 80% may actually indicate impaired oxygen extraction at the tissue level. Summary: ScvO₂ can be used as a guide for blood transfusion therapy and fluid administration in patients undergoing cardiac surgery. Furthermore, integrating ScvO₂ monitoring with lactate levels can enhance its predictive ability for poor postoperative outcomes in cardiac surgery.]]>
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