PCJN Pharmaceutical and Clinical Journal of Nusantara
Vol. 1 No. 03 (2023): PCJN: Pharmaceutical and Clinical Journal of Nusantara

Physicochemical Characterization and Phytochemical Screening of Citrus aurantifolia Lime Peel Ethanolic Extract from Kediri as Antibacterial Agent

Putri, Luluk Aniqoh Meliana (Unknown)
Febrianto, Yahya (Unknown)



Article Info

Publish Date
31 Jul 2023

Abstract

Citrus aurantifolia (Christm.) Swingle lime peel, widely discarded as agricultural waste in Kediri, East Java, Indonesia, is a promising source of bioactive compounds for antibacterial applications. Quality standardization of herbal materials is prerequisite for reproducible pharmacological activity, yet comprehensive physicochemical and microbiological characterization of lime peel simplicia from this region has not been reported. This study aimed to characterize the dried powder of C. aurantifolia lime peel collected from Kediri according to Indonesian Herbal Pharmacopoeia (IHP) standards, including microbial quality parameters (Total Aerobic Plate Count/ALT and Mold-Yeast Count/AKK), and to conduct phytochemical profiling of both simplicia and the ethanolic extract. Lime peels were cleaned, dried at 40–50°C, powdered, and characterized for water content (8.64%), water-soluble extract (26.67%), ethanol-soluble extract (18.14%), total ash (5.62%), acid-insoluble ash (0.35%), ALT (3.5 × 10³ CFU/g), and AKK (1.2 × 10² CFU/g)—all within IHP requirements. Phytochemical screening detected alkaloids, flavonoids, glycosides, saponins, tannins, and steroids/triterpenoids in both simplicia and extract. These findings establish a standardized pharmacognostic profile supporting the use of Kediri-sourced lime peel extract in evidence-based antibacterial research.

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Journal Info

Abbrev

pcjn

Publisher

Subject

Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

Description

Journal that publishes Focus & Scope research articles, which include: Pharmaceutical Biology Pharmaceutical Technology Pharmaceutical Chermistry Pharmacology Clinical Pharmacy Microbiology Pharmacy This journal is published by the Nusantara Scientific Journal , which is published March, July, and ...