Indonesian Journal of Pharmaceutical Science and Technology
Vol 13, No 1 (2026)

Standardization, Antioxidant, and Antimicrobial Activity Test of Ethanol Extract from Andiroba Bark (Carapa guianensis)

Hasanuddin, Silviana (Unknown)
Isrul, Muhammad (Unknown)
Saafi, La Ode (Unknown)
Dewi, Citra (Unknown)
Yulianingsih, Eka Putri (Unknown)
Dewi, Shafira Endah Amartya (Unknown)
Nita, Waode Adisti Elmira (Unknown)
Zainal, Mardani (Unknown)



Article Info

Publish Date
28 Feb 2026

Abstract

Most degenerative diseases are linked to excess free radicals generated by the body's metabolism or exposure to external factors. Antioxidants are used to help neutralize free radicals and treat bacterial infections. Andiroba bark (Carapa guianensis) is one of the plants used empirically by the people of the Province of Jeneponto to treat various diseases. This study aims to determine whether the ethanol extract of andiroba bark meets the standardization requirements and exhibits antioxidant activity, and to identify its ability to inhibit the growth of Staphylococcus aureus, Propionibacterium acnes, Staphylococcus epidermidis, and Escherichia coli. The results of the research showed that the results of specific and non-specific standardization of the ethanol extract from andiroba bark met the specified requirements, the ethanol extract had an antioxidant activity with an IC50 value of 15.985 μg/mL, which was included in the group of very strong antioxidants and could inhibit the growth of Staphylococcus aureus, Propionibacterium acnes, Staphylococcus epidermidis, and Escherichia coli bacteria at concentrations of 0.01 g/mL, 0.05 g/mL, and 0.1 g/mL. Overall, the ethanol extract from andiroba bark meets the standardization requirements and exhibits antibacterial activity.

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Journal Info

Abbrev

ijpst

Publisher

Subject

Computer Science & IT Medicine & Pharmacology

Description

Jurnal Sains dan Teknologi Farmasi Indonesia (IJPST) adalah publikasi ilmiah pada seluruh aspek Sains dan Teknologi Farmasi. Jurnal ini diterbitkan 3 kali setahun untuk menyediakan forum bagi apoteker, dan profesional kesehatan lainnya untuk berbagi praktik terbaik, meningkatkan jaringan kerja dan ...