Pharmascience
Vol 13, No 1 (2026): Jurnal Pharmascience

Antibiotic Use Patterns in Obstetric and Gynecological Surgery Patients: A Quantitative Descriptive Study Using ATC/DDD and DU90% Methods

Azzahra, Maryamah (Unknown)
Intannia, Difa (Unknown)
Dwi Sandi, Dita Ayulia (Unknown)
Saksono, Reni Yustiati (Unknown)
Yosita, Revina Aditya (Unknown)
Lingga, Herningtyas Nautika (Unknown)



Article Info

Publish Date
31 Mar 2026

Abstract

Surgical site infections (SSIs) are common postoperative complications in obstetric and gynecological surgery, with incidence rates up to 20% in cesarean sections. Antibiotics are the primary strategy for SSI prevention; however, antibiotic utilization patterns in this surgical setting remain poorly characterized locally. This study describes the antibiotic use profile, AWaRe classification, DDD/100 patient-days values, and DU90% segment among obstetric and gynecological surgery patients at Ulin Regional General Hospital, Banjarmasin, in 2024. A retrospective, non-experimental quantitative descriptive design was employed. Of 313 medical records reviewed, 137 met the inclusion criteria. A total of 173 antibiotic prescriptions were identified. Ceftriaxone was the most frequently used antibiotic (61.84%), with cephalosporins predominating (91.91%) and parenteral administration in 75.72% of cases. Based on the WHO AWaRe 2022 classification, 85.55% of antibiotics were in the Watch group and 13.29% in the Access group; no Reserve antibiotics were used. Ceftriaxone had the highest DDD/100 patient-days (33.74). Ceftriaxone and cefixime comprised the DU90% segment. These findings highlight a predominance of Watch-group antibiotics and support the need for targeted stewardship interventions

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Journal Info

Abbrev

pharmascience

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal Pharmascience memuat naskah hasil penelitian dan artikel review bidang kefarmasian. Naskah dapat berasal dari mahasiswa, dosen, peneliti, dan lembaga riset. Setiap naskah yang diterima redaksi Jurnal Pharmascience akan ditelaah oleh Mitra Bebestari dan Anggota Redaksi. Jurnal Pharmascience ...