Jurnal Pharmacopoeia
Vol 5 No 1 (2026): Maret 2026

Pengaruh Jenis Pemanis Terhadap Karakteristik Fisik Granul Effervescent Daun Lidah Buaya (Aloe vera L.)

Rahmatul Mutia Mutia (Jurusan Farmasi, Poltekkes Kemenkes Aceh, Aceh Besar, Aceh, Indonesia)
Hamsinah Hamsinah (Fakultas Farmasi, Universitas Muslim Indonesia, Makassar, Makassar, Indonesia)
Amelia Sari (Jurusan Farmasi, Poltekkes Kemenkes Aceh, Aceh Besar, Aceh, Indonesia)
Ernita Silviana (Jurusan Farmasi, Poltekkes Kemenkes Aceh, Aceh Besar, Aceh, Indonesia)
Burdah Burdah (Jurusan Farmasi, Poltekkes Kemenkes Aceh, Aceh Besar, Aceh, Indonesia)
Rima Hayati (Jurusan Farmasi, Poltekkes Kemenkes Aceh, Aceh Besar, Aceh, Indonesia)



Article Info

Publish Date
30 Mar 2026

Abstract

Aloe vera L. has considerable potential as a natural ingredient for oral preparations; however, the inherent bitterness of its leaf powder limits patient acceptability. Effervescent granules were selected to improve convenience and palatability, in which sweeteners may influence both taste and physical performance. This study aimed to evaluate the effect of sweetener type on the physical characteristics of Aloe vera effervescent granules. Granules were prepared by wet granulation using aspartame (F1) and stevia (F2). Evaluations included organoleptic properties, moisture content, flow time, angle of repose, and dispersion time. Statistical analysis was performed using the Mann–Whitney U test for moisture content and Welch’s t-test for other parameters. Both formulations met general quality requirements for effervescent granules. No significant differences were observed in moisture content and dispersion time (p > 0.05). However, flow time and angle of repose differed significantly (p < 0.05). F1 showed faster flow time (1.55 ± 0.05 s) and lower angle of repose (20.40 ± 1.07°) compared to F2 (2.30 ± 0.26 s; 24.70 ± 1.35°), indicating better flowability. These findings suggest that sweetener type significantly influences granule flow properties but not moisture stability or dispersion performance

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Journal Info

Abbrev

pharmacopoeia

Publisher

Subject

Medicine & Pharmacology Public Health

Description

Jurnal Pharmacopoeia (JPharmaco) O-ISSN: 2809-4573 is an official journal published by Pharmacy Program, Health Analyst Department, Health Polytechnic of Bengkulu which the articles can be accessed and downloaded online by the public (open access journal). This journal is a national peer-reviewed ...