Kwaghe International Journal of Sciences and Technology
Vol 1 No 1 (2024): Kwaghe International Journal of Sciences and Technology

Antibacterial Effect of Methanol Extract of Newbouldia laevis Leaves on Some Selected Resistant Pathogen on Synthesised Drugs

Kerenhappuch Isaac Umaru (Unknown)
Egeonu Stephen Ugoeze (Unknown)
Akafa Andes Tansaba (Unknown)
Chakfa Nanmar (Unknown)
Tyem Lawal Danjuma (Unknown)
Isaac John Umaru (Unknown)



Article Info

Publish Date
19 Jul 2024

Abstract

Newbouldia laevis is a tropical plant belonging to the family of Bignoniaceae. It is among the most useful plants in Africa. Historically medicinal plants have been provided a good source of inspiration for novel therapeutic drugs which has made a large contribution to health and well-being of humans. It has been used over the years to as curative agents against many infections and have been exploited in the traditional medicine with their curative potentials. Material and methods: The leaves of Newbouldia laevis was bought from a local market in Wukari, Taraba State. The leaves of Newbouldia laevis was chop into pieces, air-dried for four days and then pulverized into fine powder. About 250 g of the powdered bark extracted with 2 L of ethanol using maceration method for 72 hrs. The crude extracts of Newbouldia laevis was used in antibacterial assay. The results observed demonstrate that the Newbouldia leaves methanol crude extract possesses concentration-dependent antibacterial activity against both Gram-positive resistant bacteria (Staphylococcus aureus) and Gram-negative (Escherichia coli, Klebsiella pneumonia) bacteria. The increasing inhibition zones with higher concentrations suggest a potential dose-response relationship.

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Journal Info

Abbrev

KIJST

Publisher

Subject

Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Environmental Science Law, Crime, Criminology & Criminal Justice Social Sciences

Description

Kwaghe International Journal of Sciences and Technology aims to publish rigorous, peer-reviewed scholarship that advances natural sciences, agriculture, and technology through high-quality quantitative, qualitative, and mixed-methods research. The journal prioritizes methodological transparency, ...