Precision Medicine: A Comprehensive Review of Advances and Challenges on Implementaion Integrated Management of Childhood Illness

Joaquim Pinto (Universidade Nacional Timor Loro Sa'e)
Eugenia Carvalho de Araujo (Universidade Nacional Timor Loro Sa'e, East Timor)
Carlos Boavida Tilman (Universidade Nacional Timor Loro Sa'e, East Timor)
Adelina Pinto (Universidade Nacional Timor Loro Sa'e, East Timor)
Manuel Fransisco da Costs (Universidade Nacional Timor Loro Sa'e, East Timor)

SEHAT
Vol. 1 No. 1 (2024): Medical Studies and Health Journal (SEHAT)

Precision medicine is a rapidly growing paradigm in the understanding of disease, especially in pediatric medicine. This article evaluates significant advances in genomics and gene-based technologies, and their impact on personalized diagnosis and therapy for children. The integration of genetics with epidemiology opens up new opportunities in understanding gene-environment interactions and disease disparities, which have a direct impact on childhood disease management. Nevertheless, challenges such as equitable access to genetic innovation worldwide still need to be overcome. Recommendations include improved research methods, cross-country collaboration, as well as assessment of long-term effects and greater patient involvement in clinical decision-making.