Paediatrica Indonesiana
Vol 45 No 3 (2005): May 2005

The efficacy of single-dose albendazole for the treatment of ascariasis

Deddy S Putra (Unknown)
W Dalimunthe (Unknown)
M Lubis (Unknown)
S Pasaribu (Unknown)
Chairuddin Lubis (Unknown)



Article Info

Publish Date
10 Oct 2016

Abstract

Objective This study aims to assess the efficacy of single-dosealbendazole in treating mild, moderate, and severe ascariasis.Methods Stool specimens were collected from randomly selectedelementary school children in Suka village, Sumatera Utara, fromMarch to April 2002. Based on the number of eggs per gram feces(NEPG), samples were categorized as mild (NEPG < 7000), mod-erate (NEPG 7000-35,000), or severe (NEPG > 35,000) ascari-asis. All subjects then received 400 mg albendazole orally. NEPGcount was repeated on the 7 th , 14 th , 21 st and 28 th day after treat-ment. The chi-square test was used to compare cure rates be-tween subjects with mild, moderate, and severe ascariasis. TheANOVA and Kruskal-Wallis tests were employed to analyze quan-titative data.Results From the 134 specimens collected, we found mild ascari-asis in 57 (42.5%), moderate ascariasis in 57 (42.5%), and severeascariasis in 20 (15%). There was no significant difference be-tween the three groups in NEPG after treatment (P>0.05). Thecure rate and egg reduction rate on day 28 after treatment was 100%.Conclusion A single dose of 400 mg albendazole is effective forthe treatment of mild, moderate, and severe ascariasis.

Copyrights © 2005






Journal Info

Abbrev

paediatrica-indonesiana

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of ...