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All Journal Paediatrica Indonesiana The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Deddy S Putra
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Health Professions Medicine & Pharmacology

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The efficacy of single-dose albendazole for the treatment of ascariasis Deddy S Putra; W Dalimunthe; M Lubis; S Pasaribu; Chairuddin Lubis
Paediatrica Indonesiana Vol 45 No 3 (2005): May 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi45.3.2005.118-22

Abstract

Objective This study aims to assess the efficacy of single-dosealbendazole in treating mild, moderate, and severe ascariasis.Methods Stool specimens were collected from randomly selectedelementary school children in Suka village, Sumatera Utara, fromMarch to April 2002. Based on the number of eggs per gram feces(NEPG), samples were categorized as mild (NEPG < 7000), mod-erate (NEPG 7000-35,000), or severe (NEPG > 35,000) ascari-asis. All subjects then received 400 mg albendazole orally. NEPGcount was repeated on the 7 th , 14 th , 21 st and 28 th day after treat-ment. The chi-square test was used to compare cure rates be-tween subjects with mild, moderate, and severe ascariasis. TheANOVA and Kruskal-Wallis tests were employed to analyze quan-titative data.Results From the 134 specimens collected, we found mild ascari-asis in 57 (42.5%), moderate ascariasis in 57 (42.5%), and severeascariasis in 20 (15%). There was no significant difference be-tween the three groups in NEPG after treatment (P>0.05). Thecure rate and egg reduction rate on day 28 after treatment was 100%.Conclusion A single dose of 400 mg albendazole is effective forthe treatment of mild, moderate, and severe ascariasis.
The Role of Supporting Examinations on the Diagnosis of Chronic Diarrhea in Children Deddy S Putra; Muzal Kadim; Pramita G D; Badriul Hegar; Aswitha Boediharso; Agus Firmansyah
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 8 ISSUE 2 August 2007
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/82200735-39

Abstract

Background: Etiology of chronic diarrhea can be established through non-invasive examination such as stool examination and stool culture. Colonoscopy is an invasive Method, which is occasionally needed to discover the etiology of chronic diarrhea. Objective: To recognize the characteristics of chronic diarrhea based on stool examination and colonoscopy results. Methods: Descriptive study on patients with chronic diarrhea who came to Cipto Mangunkusumo hospital since 1 June to 31 August 2005. Laboratory tests were conducted in accordance with clinical indication. Data was presented in distribution tables. Results: There were 41 patients with chronic diarrhea. Stool examination were performed only in 38 patients with negative-gram infection (86.8%). Stool cultures were performed in 27 patients with positive results of non-pathogenic Escherichia coli (85.2%). Stool parasite examination and concentration tests were performed in 17 patients, with 47.0% positive results as follow: Microsporidia 29.4%, Blastocystis hominis 11.8% and Giardia lamblia 5.9%. Colonoscopy examinations were performed in 6 patients and all patients indicated ulcerative colitis appearance with 50% histopathological impression of infective colitis. Conclusion: Stool examination in chronic diarrhea primarily indicates positive infection. Bacterial stool culture mostly includes non-pathogenic Escherichia coli, while parasite stool examination largely includes Microsporidia. Biopsy examination tends to reveal infective colitis. Keywords: chronic diarrhea, parasite stool, colonoscopy
Co-Authors Agus Firmansyah Agus Firmansyah Aswitha Boediharso Badriul Hegar Badriul Hegar Chairuddin Lubis M Lubis Muzal Kadim Pramita G D S Pasaribu W Dalimunthe