Pengaruh Perbandingan Pelarut Etanol-Air Terhadap Kadar Senyawa Fenolat Total dan Daya Antioksidan dari Ekstrak Daun Sirsak (Annona muricata L.)

Rivai, Harrizul
S, Ernita Widiya
Rusdi, Rusdi

Jurnal Sains dan Teknologi Farmasi
Vol 18 No 1 (2013)

A Study has been conducted to determine the influence of ethanol-water ratio on the concentration of total phenolic compounds and antioxidant activities of extract of soursop leaves. Ethanol-water ratio used were ethanol 96%, ethanol-water 2:1 and ethanol-water 1:1. Concentration of phenolic compounds were determined by Folin-Ciocalteau method and antioxidant activities were detemined by diphenylpicrylhydrazyl method. Results showed that the ratio of ethanol-water had a significant influence on the total content of phenolic compounds (p < 0.05). Highest content of total phenolic compound was obtained by using ethanol-water 1:1, whereas the highest antioxidant activity was obtained by using ethanol 96%.