<![CDATA[Influenza is a viral infection that can cause serious complications and spread rapidly. Antivirals such as oseltamivir, zanamivir, peramivir and baloxavir are effective at reducing the duration of illness if given within the first 48 hours. However, viral mutations can lead to resistance to antivirals, decreasing the effectiveness of treatment. This review analyzes antiviral resistance and effectiveness based on a literature review from various sources. Results show that resistance to oseltamivir and amantadine is a major challenge, and antiviral effectiveness is affected by the timing of administration, patient condition, and viral mutations. Several strategies, including antiviral combinations, new drug development, herbal plants, and vaccination, were developed to overcome resistance, but none have been fully effective. Monitoring viral resistance and developing adaptive treatment strategies are needed to improve influenza control.]]>
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