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Nelis Hernahadini
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Jurnal Biodiversitas dan Bioteknologi
Published by Universitas Muhammadiyah Bandung
ISSN : -     EISSN : 30891671     DOI : -
Core Subject :
BIODIVERSE: Jurnal Biodiversitas dan Bioteknologi, merupakan salah satu jurnal ilmiah yang diterbitkan oleh Program Studi Bioteknologi yang memuat artikel penelitian dan revew jurnal dalam bidang Biodiversitas dan Bioteknologi (Biodiversitas, Struktur dan Fungsi Sel; Biokimia Sel, Protein dan Enzim, Genetika Terapan dan Molekuler; Genomik dan Proteomik; Mikrobiologi Terapan; Bioproses; Kultur Jaringan, Sel Punca; Bioinformatika; Virologi; serta Bioteknologi Terapan
Arjuna Subject : -
Articles 24 Documents
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Aplikasi Multilayered Edible Coating Dengan Variasi CaCl2 Pada Buah Tomat (Solanum lycopersicum L.) Adzani Ghani Ilmannafian; Almira Ulimaz; Mariatul Mariatul Kiptiah; Muhammad Indra Darmawan; Nor Halysa
Jurnal Biodiversitas dan Bioteknologi Vol 1 No 1 (2024): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
Publisher : Jurnal Biodiversitas dan Bioteknologi

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Abstract

Edible coating merupakan suatu lapisan tipis yang dibuat dari bahan yang dapat dimakan (edible), Dibentuk untuk melapisi suatu produk pangan sedangkan Multilayered merupakan pelapis anti mikroba berlapis-lapis yang dapat dimakan dan berpengaruh terhadap umur simpan dan kualitas buah. Penelitian ini bertujuan untuk menganalisis kualitas buah tomat (Solanum lycopersicum L.) dengan penggunaan Multilayered edible coating. Metode penelitian yang dilakukan adalah menggunakan metode eksperimental dengan sekian perlakuan dengan konsentrasi cacl2 0,5 gram, 1 gram dan 1,5 gram. Pengujian yang digunakan yaitu uji susut bobot, uji vitamin c, uji pH dan dengan uji anova dengan perlakuan variasi CaCl2 yang berbeda. Berdasarkan hasil penelitian kualitas buah tomat terbaik dengan penggunaan multilayered edible coating pada konsentrasi CaCl2 tberpengaruh terhadap susut bobot dan kurang berpengaruh pada vitamin C dan nilai pH . Berdasarkan hal tersebut dibutuhkan teknologi untuk mempertahankan mutu buah tomat dengan membuat multilayered edible coating berbahan dasar pati pisang tundang, CMC, CaCl2, dan kitosan. Kata kunci: Edible coating; CaCl2; Susut bobot; Vitamin C; Tomat Edible coating merupakan suatu lapisan tipis yang dibuat dari bahan yang dapat dimakan (edible), Dibentuk untuk melapisi suatu produk pangan sedangkan Multilayered merupakan pelapis anti mikroba berlapis-lapis yang dapat dimakan dan berpengaruh terhadap umur simpan dan kualitas buah. Penelitian ini bertujuan untuk menganalisis kualitas buah tomat (Solanum lycopersicum L.) dengan penggunaan Multilayered edible coating. Metode penelitian yang dilakukan adalah menggunakan metode eksperimental dengan sekian perlakuan dengan konsentrasi cacl2 0,5 gram, 1 gram dan 1,5 gram. Pengujian yang digunakan yaitu uji susut bobot, uji vitamin c, uji pH dan dengan uji anova dengan perlakuan variasi CaCl2 yang berbeda. Berdasarkan hasil penelitian kualitas buah tomat terbaik dengan penggunaan multilayered edible coating pada konsentrasi CaCl2 tberpengaruh terhadap susut bobot dan kurang berpengaruh pada vitamin C dan nilai pH . Berdasarkan hal tersebut dibutuhkan teknologi untuk mempertahankan mutu buah tomat dengan membuat multilayered edible coating berbahan dasar pati pisang tundang, CMC, CaCl2, dan kitosan. Kata kunci: Edible coating; CaCl2; Susut bobot; Vitamin C; Tomat
Review Artikel: Model Biorekognisi Berbasis Antibodi (Immunodiagnostic) Pada Biosensor Untuk Deteksi Awal Kanker Payudara Syifa Lutfiah; Nelis Hernahadini
Jurnal Biodiversitas dan Bioteknologi Vol 1 No 1 (2024): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
Publisher : Jurnal Biodiversitas dan Bioteknologi

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Abstract

Kanker payudara adalah salah satu kanker penyebab kematian tertinggi pada wanita di seluruh dunia. Hal ini disebabkan penderita kanker payudara baru mendapatkan pelayanan kesehatan saat kanker sudah stadium lanjut. Diagnosis dini kanker sangat penting untuk keberhasilan pengobatan penyakit karena kanker akan jauh lebih mudah disembuhkan pada tahap awal. Strategi biosensor inovatif akan memungkinkan pengujian kanker untuk dilakukan lebih cepat, murah, dan andal. Imunosensor adalah jenis biosensor berbasis solid-state afinitas dimana analit target spesifik, antigen (Ag), dideteksi dengan pembentukan imunokompleks yang stabil antara antigen dan antibodi sebagai agen penangkap (Ab) yang menghasilkan sinyal terukur untuk transduser. Penelitian ini menggunakan analisis pada beberapan artikel yang telah dipublikasikan di jurnal Internasional terakreditasi dengan skematik dan kemajuan biorekognisi berbasis antibodi sebagai fokus utama penelitian. Diantara beberapa publikasi tersebut model biorekognisi antibody monoclonal yang di integrasikan dengan nanopartikel dengan HER2 biomarker melalui deteksi pada darah menggunakan prinsip elektrokimia , optik, dan piezoelektrik . Temuan ini menunjukkan biosensor yang dikembangkan menunjukan hasil klinis yang baik sehingga layak diaplikasikan secara massif untuk deteksi dini kanker payudara yang diharapkan mampu meningkatkan kelangsungan hidup pasien
Epidemiologi, Patofisiologi, dan Faktor Resiko Human Papilloma Virus Risma Nurjanah; Nurul Halisa; Wulan Pertiwi
Jurnal Biodiversitas dan Bioteknologi Vol 1 No 1 (2024): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
Publisher : Jurnal Biodiversitas dan Bioteknologi

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Abstract

Human Papillomavirus is a type of virus that mostly infects the reproductive tract. Men and women who have high sexual activity have a greater chance of being infected with this virus. HPV is a virus that causes many cancers, one of which is cervical cancer which is one of the main causes of death in cancer patients. HPV infection is a serious problem, especially for poor and developing countries, because poverty and laziness are the main causes of the spread of sexually transmitted diseases. One form of prevention that is widely used in various countries is the HPV vaccine program.
Aplikasi Wolbachia Sebagai Kontrol Biologi Demam Berdarah Dengue : Kajian Literatur Fadly Hidayaturochman; Aghniya Nur Rizka Fadila; Haryanto Haryanto
Jurnal Biodiversitas dan Bioteknologi Vol 1 No 1 (2024): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
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Abstract

Dengue fever is a disease transmitted by the Aedes aegypti mosquito. The infection rate in Indonesia in 2023 reached 42,690 people and 317 people died. In fact, Indonesia has one of the highest rates among other Southeast Asian countries. The use of insecticides in handling these cases causes mosquito resistance and air pollution. One of the efforts in controlling Dengue transmission can be done by biological control with the use of endosymbionts, namely Wolbachia. Therefore, the purpose of this literature review is to determine the preparation of Wolbachia-infected mosquitoes and their effectiveness as biological control of DHF, as well as the mechanism of Wolbachia mosquitoes in controlling DHF. The method of writing this literature review used online literature searches sourced from Google Scholar, Pubmed and Science Direct. Wolbachiainfected Aedes aegypti mosquitoes were prepared by confirming positive Wolbachia-infected mosquitoes using the PCR method, and then cultured in the laboratory. Mosquito eggs from matings are sorted manually, then Wolbachia bacteria are injected into the eggs using an automated microinjector, Wolbachiainfected mosquito larvae are bred, and quality control is conducted prior to release. Wolbachia mosquito technology has been proven to reduce Dengue infection by 77.1% and prevent hospitalization by 83% in Yogyakarta City.
The Potensi Mikroalga Laut, Chlorella vulgaris, dalam Menghasilkan Listrik Qori Atur R. Suhada; Aditya Indra Gunawan; Tiwi Sartika; Hasna Labib Lathifah; Marsya Naranissa Puteri; Maya Amini Sukma; Nadilla Suci Nugraha; Rosi Ainin Faqihah; Tiara Zahira
Jurnal Biodiversitas dan Bioteknologi Vol 1 No 1 (2024): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
Publisher : Jurnal Biodiversitas dan Bioteknologi

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Abstract

Electrical energy is energy that comes from an electric charge that creates a static electric field or the movement of electrons in electrical conductors or ions (positive or negative) in liquids or substances in the form of gases. One of the sources of renewable electrical energy can be obtained from marine microalgae through the process of photosynthesis, called Biophotovoltaics. The electrical energy produced by these marine microalgae can be channeled to power electronic devices. Chlorella vulgaris is a photosynthetic microorganism that can be used in biophotovoltaics systems. The purpose of this observation is to utilize microalgae as a renewable energy source and to develop the potential of microalgae, especially green algae. The method used is to create a Biophotovoltaics system utilizing 2 glass tubes filled with microalgae cultures which are connected to an electrical circuit using aluminum and steel electrodes. The experiments carried out produced electricity of 2.5V from 2 liters of microalgae culture that had previously been made. The amount of electric voltage obtained from the microalgae is strongly influenced by the biomass it produces during photosynthesis.
Sindrom Rett: Kelainan Genetik Penyebab Disabilitas Intelektual Nisa Ihsani; Elisca Nurhayati; Tabina Khalishah Dzikra Dzakirah; Yesi Repani
Jurnal Biodiversitas dan Bioteknologi Vol 1 No 1 (2024): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
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Abstract

Rett Syndrome (RTT) is a rare genetic disorder affecting early neurological development that has a mutation linked to the X chromosome in the MECP2 gene that codes for methyl CpG-binding protein 2, resulting in loss of function. Typical symptoms of Rett Syndrome are impaired communication and loss of speech, loss of hand use, repetitive, involuntary hand movements such as hand washing, loss of mobility, or difficulty walking. Rett Syndrome is very rare in Indonesia. It occurs in 1 in 10,000 - 15,000 children. A specific treatment cannot treat Rett Syndrome. However, treatment can be done for the symptoms, including sleep disorders, eating disorders, seizures, and self-injurious behavior. Trefinetide is one treatment that is specific to the main symptoms of Rett Syndrome.
Karakterisasi Bakteri Kombucha Teh Melati dan Teh Hijau sebagai Agen Pupuk Hayati Muhammad Fauzi; Nisa Ihsani; Rois Suriyah
Jurnal Biodiversitas dan Bioteknologi Vol 1 No 1 (2024): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
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Production of fermented tea or kombucha can produce waste in the form of brown scoby. This waste can be used as a source of biological fertilizer agents for plants. This research aims to identify bacteria that act as biological fertilizer agents contained in kombucha scoby waste. The research method was the isolation and characterization of bacteria grown on Pikovskaya solid media to determine the biochemical reactions of groups of phosphate solubilizing bacteria and sedirophore bacteria on Fe-CAS media. The results of the research showed that there were phosphate solubilizing bacteria from samples K1 and K2 with the criteria that the colonies formed a clear clear zone (halozone) and K1 showed positive as a siderophore producing bacteria with orange colonies formed.
Review Artikel: Resistensi HIV dan Mekanisme Kerja Antiretroviral Siti Fatimah Azzahra; Muhammad Farid Maksum
Jurnal Biodiversitas dan Bioteknologi Vol 2 No 1 (2025): Vol 2 No 1 (2025): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
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HIV (Human Immunodeficiency Virus) is a virus that attacks the human immune system, especially CD4 cells which are important for the body's defense against infection. Untreated HIV infection can lead to AIDS (Acquired Immunodeficiency Syndrome), a condition in which the immune system is very weak and susceptible to various opportunistic infections and cancers. HIV has become one of the most challenging global health problems, with millions of people infected and dying each year. One of the greatest advances in HIV treatment is the development of antiretroviral therapy (ARV). This therapy uses a combination of several drugs to suppress viral replication in the body, slow the progression of the disease, and prolong the patient's life expectancy. However, the long-term success of this therapy is threatened by the emergence of resistance to antiretroviral drugs. The mechanism of action of ARVs involves several steps in the HIV life cycle, including protease inhibitors, reverse transcriptase inhibitors, and integrase inhibitors. This study uses a literature review method and involves 15 relevant journals to discuss HIV resistance and the mechanism of action of ARVs. The results of the study showed that ARV therapy is effective in improving the health of HIV patients, but the effectiveness and retention of therapy are greatly influenced by the time of therapy initiation, type of therapy, and disclosure of the patient's HIV status.
Review Artikel: Perkembangan Biosensor Dalam Mendeteksi Kandungan Babi (Sus scrofa) pada Produk Pangan untuk Verifikasi Kehalalan Silfa Zakiyah; Siti Fatimah Azzahra
Jurnal Biodiversitas dan Bioteknologi Vol 1 No 2 (2024): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
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Abstract

Food processing in Indonesia and countries around the world is becoming increasingly complex. Food management must meet quality requirements, including nutritional fulfillment, safety and halal food products. Various analytical methods have been developed to test various products, both physically, chemically and biologically. Therefore, laboratory testing is needed to detect the presence of contaminants and non-halal ingredients in food products. This research discusses the detection of pork content in food products to support halal authentication. PCR and Biosensor methods are efficient and sensitive ways to ensure that food products are free from pork contamination. The Polymerase Chain Reaction (PCR) method allows the amplification of specific DNA from pigs, detecting even traces of DNA with high accuracy. Meanwhile, biosensors, which use antibodies or other biomolecular components, are able to detect pork proteins with high sensitivity through specific interactions with the target analyte. The method used is a literature review, conducting studies from various sources with the help of databases such as Connected Papers, ResearchGate, and Google Scholar with keywords such as "Detection of pork in food", "Regulation of halal food products", and "Biosensor for detecting pork content in food". This literature study used 40 journals selected based on the information needed
Review: Teknologi Biosensor dalam Mendeteksi Senyawa Antidiabetes pada Tanaman Muhammad Farid Maksum; Nurhaifa Azzahra; Nelis Hernahadini
Jurnal Biodiversitas dan Bioteknologi Vol 2 No 2 (2025): Biodiverse: Jurnal Biodiversitas dan Bioteknologi
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Type 2 diabetes is a serious, widespread health problem worldwide that causes reduced quality of life, mortality, mortality and significant economic burden. The high number of diabetes sufferers in Indonesia has encouraged the development of anti-diabetic drugs, including those derived from plants used as traditional medicine. The role of biosensors in detecting antidiabetic compounds in plants is very important because they can provide fast, accurate and sensitive methods for biochemical analysis. The purpose of this review is to provide an overview of biosensor technology used for detecting antidiabetic compounds in plant leaves by discussing the general principles of biosensors, their mechanisms using electrochemical biosensor devices, paper-based biosensors, and microzone plastic-based biosensors. The literature study was carried out by searching articles from various leading journal databases, such as PubMed, Google Scholar, and ResearchGate. A review was carried out regarding biosensor devices as anti-diabetic compound detectors with three technical types, namely electrochemical, paperbased and microzone plastic-based. Based on sensitivity and other advantages, microzone plastic-based biosensors are the best biosensors compared to the other two biosensors. The use of microzone plastic-based biosensors is also very simple, requiring only the placement of the sample on the detection area, after which the compound can be detected through the scanner/sensor features embedded in the device

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