Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan
Vol 17, No 1 (2026): Syifa Medika : Jurnal Kedokteran dan Kesehatan

The Effect of Cinnamon Extract on Reducing Blood Glucose Levels in Alloxan-Induced Mice.

Cleo Aurelia Moza (Unknown)
Yanti Rosita (Universitas Muhammadiyah Palembang)
Rury Tiara Oktariza (Universitas Muhammadiyah Palembang)
Putri Erlyn (Universitas Muhammadiyah Palembang)



Article Info

Publish Date
19 May 2026

Abstract

Diabetes mellitus is a metabolic disorder with a globally increasing incidence; however, existing treatments remain limited by undesirable side effects and challenges in achieving optimal blood glucose levels. Natural products offer potential advantages, including lower toxicity profiles and the ability to modulate multiple metabolic pathways. Cinnamon is a natural ingredient known to contain various bioactive compounds with antidiabetic properties. This study aims to evaluate the effects of ethanol cinnamon extract (Cinnamomum spp.) on reducing fasting blood glucose (FBG) levels in alloxan-induced male Webster strain mice. An experimental method with a pre-post test control group design was employed. Five test groups were established: a negative control (distilled water), a positive control (metformin 1.3 mg), and three doses of cinnamon extract (150 mg/kg BW, 200 mg/kg BW, and 250 mg/kg BW). The results demonstrated that the administration of 200 mg/kg BW of cinnamon extract exerted an antihyperglycemic effect by significantly decreasing FBG levels in alloxan-induced mice (p

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Journal Info

Abbrev

syifamedika

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

Description

Syifa MEDIKA published by Faculty of Medicine, University of Muhammadiyah Palembang is a peer-reviewed journal that published two times a year: September and March. Syifa MEDIKA is a national peer-reviewed and open access journal. We accept original article, case report, and literature review from ...