Treatment monitoring is crucial for preventing drug resistance, using both clinical and laboratory approaches. One parameter receiving increasing attention is the monocyte-to-lymphocyte ratio (MLR), which reflects the body's immune response to infection. Several studies have shown an increase in MLR in active TB patients, but its role as a predictive indicator of pulmonary TB treatment outcomes has not been fully studied. This study aimed to evaluate the value of MLR in predicting treatment success in pulmonary tuberculosis (TB) patients. This was a descriptive study with a cross-sectional design, using a population of smear-positive pulmonary tuberculosis patients undergoing treatment. A total of 40 newly diagnosed TB cases were randomly selected. Three ml of patient blood was collected in EDTA vacuum tubes and hematological parameters were analyzed. Blood was then drawn from the same patients after 1 month of antituberculosis treatment, and hematological parameters were analyzed. Pre- and post-treatment parameters were compared and analyzed using appropriate statistics. The results showed that patients diagnosed with pulmonary TB did not experience significant changes in monocyte-to-lymphocyte ratio (MLR) values before and after treatment.
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