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All Journal Jaringan Laboratorium Medis Jurnal Ners International Journal of Educational and Life Sciences (IJELS)
Fitriani Kahar
Poltekkes Kemenkes Semarang
Religion Humanities Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Public Knowledge About Pulmonary Tuberculosis (Tb): a Cross-Sectional Study in Indonesia Fitriani Kahar; Irnawati; Muh Yusuf; Ririh Jatmi; Abdul Salam; Abdul Wadood
International Journal of Educational and Life Sciences Vol. 1 No. 2 (2023): October 2023
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59890/ijels.v1i2.521

Abstract

Tuberculosis or TB is a disease caused by the acid-fast bacillus Mycobacterium tuberculosis. Transmission of the disease through inhalation of air droplets infected with Mycobacterium tuberculosis bacteria. The aim of this research is to determine the description of public knowledge about TB disease in terms of concepts, facts and procedures. The research method used was descriptive research with a cross-sectional design to see a picture of public knowledge about TB disease. The research population was people from 3 villages, namely Tlogosari Kulon, Tlogosari Wetan and Bangetayu Wetan. The sample size was 176 people chosen randomly. Data collection techniques use questionnaires and interviews with respondents. The research results obtained showed that the majority of respondents' knowledge was in the high category, namely 160 frequency or 90.9%. Concept knowledge shows a high category, namely 162 frequencies or 92%. Knowledge Facts shows a high category, namely 152 frequencies or 86.4%. Procedural knowledge shows a high category, namely 127 frequencies or 72.2%. The conclusion shows that most of the public's knowledge is in the high category.
Perbandingan Nilai Rasio Monosit Terhadap Limfosit (MLR) Pada Pasien Tuberkulosis Sebelum Dan Setelah Pengobatan Ririh Jatmi Wikandari; Qurrotu A’yuni Auliya; Fitriani Kahar; Siti Nuryani; Sistiyono Sistiyono
Jurnal Ners Vol. 10 No. 2 (2026): APRIL 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i2.55141

Abstract

Treatment monitoring is crucial for preventing drug resistance, using both clinical and laboratory approaches. One parameter receiving increasing attention is the monocyte-to-lymphocyte ratio (MLR), which reflects the body's immune response to infection. Several studies have shown an increase in MLR in active TB patients, but its role as a predictive indicator of pulmonary TB treatment outcomes has not been fully studied. This study aimed to evaluate the value of MLR in predicting treatment success in pulmonary tuberculosis (TB) patients. This was a descriptive study with a cross-sectional design, using a population of smear-positive pulmonary tuberculosis patients undergoing treatment. A total of 40 newly diagnosed TB cases were randomly selected. Three ml of patient blood was collected in EDTA vacuum tubes and hematological parameters were analyzed. Blood was then drawn from the same patients after 1 month of antituberculosis treatment, and hematological parameters were analyzed. Pre- and post-treatment parameters were compared and analyzed using appropriate statistics. The results showed that patients diagnosed with pulmonary TB did not experience significant changes in monocyte-to-lymphocyte ratio (MLR) values ​​before and after treatment.
Hubungan Kadar Kalium dan Kadar Ureum Terhadap Jenis Obat Baru pada Pasien Tuberkulosis Resistan Obat (TB RO) Sasha Marwah Anggita; Nurul Qomariyah; Fitriani Kahar
Jaringan Laboratorium Medis Vol 6 No 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.11388

Abstract

The use of new types of drugs in RO TB patients will cause disturbances in the body's electrolytes, especially potassium levels, as well as disturbances in urea levels caused by the excretion of urea that is retained in the body. Continuous increases in urea in the body result in the kidneys not being able to work optimally. The aim of this study was to determine the relationship between potassium levels and urea levels on new types of drugs in RO TB patients. The research method used is analytical observational with a cross sectional approach. This research was conducted on 16 February – 16 March 2023 with research subjects being RO TB patients who received treatment with a new type of drug at the Lung Hospital dr. Ario Wirawan Salatiga as many as 21 respondents using a sampling technique that is the total population. Potassium levels were measured using the ISE (Ion Selective Electrode) method and urea levels used the enzymatic UV test method. The data was then processed using the Shapiro-Wilk normality test, then continued with prerequisite tests (crosstab test and homogeneity test) then continued with hypothesis testing, because my data scale was ratio and nominal, the alternative test used was the Chi-Square Test. The equipment test results obtained a homogeneity test with a P value of 0.698 and 0.610 (>0.05), meaning the data was homogeneous. The test results for the relationship between potassium and urea levels on new types of drugs for RO TB patients were Chi-Square hypothesis test results with a P value of 0.152 and 0.384 (> 0.05) means there is no relationship between potassium levels and urea levels on new types of drugs in RO TB patients. The results show that the TB drugs bedaquiline and delamanid do not cause kidney function disorders so that RO TB patients can consume these TB drugs regularly.
Co-Authors Abdul Salam Abdul Wadood Irnawati Muh Yusuf Nurul Qomariyah Qurrotu A’yuni Auliya Ririh Jatmi Ririh Jatmi Wikandari Sasha Marwah Anggita Sistiyono Sistiyono Siti Nuryani