Journal of Health and Therapy
Vol. 5 No. 2 (2026): Journal of Health and Therapy

Peran sentinel node pada kanker ginekologi

Fitriyadi Kusuma (Fakultas Kedokteran, Universitas Indonesia-Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo)
Marshaly Safira Masrie (Fakultas Kedokteran, Universitas Indonesia-Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo)
Geraldus Sigap Gung Binathara (Fakultas Kedokteran, Universitas Indonesia)
Abdul Hafiidh Surya Putra (Fakultas Kedokteran, Universitas Indonesia)
Kemal Akbar Suryoadji (Fakultas Kedokteran, Universitas Indonesia)



Article Info

Publish Date
30 Mar 2026

Abstract

This review evaluated the role of sentinel lymph node mapping in early-stage gynecologic cancers, cervical, endometrial, and vulvar, as a staging approach that balanced diagnostic accuracy and patient safety. The search methods assembled evidence from major clinical trials and cohort studies on detection performance, diagnostic accuracy, and surgical morbidity compared with systematic lymphadenectomy. The findings indicated that this mapping achieved high detection rates with adequate sensitivity and reduced operative time, blood loss, and risks of lymphedema, lymphocele, and neurovascular injury. In cervical and endometrial cancer, multicenter and prospective studies demonstrated comparable oncologic safety alongside lower postoperative complications, whereas in vulvar cancer, a strategy based on a negative sentinel node reduced groin morbidity without compromising disease control in selected lesions. Tracer approaches, including radioisotopes, blue dye, and indocyanine green fluorescence, together with enhanced assessment through in-depth histopathology, supported broad clinical adoption. Overall, this review concluded that sentinel lymph node mapping was appropriate for routine use in suitable cases, provided bilateral mapping and standardized pathological evaluation.

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Journal Info

Abbrev

jht

Publisher

Subject

Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Description

Journal of Health and Therapy [E-ISSN 2808-7747 ] is a peer-reviewed scientific journal that publishes high-quality manuscripts with both basic and applied emphasis, covering theoretical and experimental research that contributes to the advancement of health and therapeutic sciences. The journal ...