Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ
Vol. 9 No. 1 (2026): Jurnal Farmasi Medika/Pharmacy Medical Journal

EFEKTIVITAS EKSTRAK BUAH SALAK (Salacca zalacca) TERHADAP PROFIL TRIGLISERIDA TIKUS PUTIH DENGAN PENYAKIT HATI BERLEMAK NON ALKOHOL

Olvie Syenni Datu (Sam Ratulangi University)
Jainer Pasca Siampa (Unknown)
Jullianri Sari Lebang (Unknown)



Article Info

Publish Date
09 Jun 2026

Abstract

Hypertriglyceridemia is a condition of elevated triglyceride levels in the blood. High triglyceride levels in the blood can increase the risk of heart disease. High triglyceride levels are caused by consumption of high-fat foods, obesity, and metabolic syndrome. Snake fruit is a fruit rich in antioxidants and plays a role in degenerative diseases. Snake fruit potential to development as an alternative in treatment. This study aims to test the antihypertriglyceremic activity in rats induced by a high-fat diet using a mixture of quail eggs and used cooking oil, and then the rats were treated with 10%, 20%, and 40% snake fruit extract. The data obtained showed that the administration of snake fruit extract could reduce the triglyceride levels of rats induced by a high-fat diet back to normal levels of <150mg/dL compared to the group induced by a high-fat diet and not treated (negative control). These results show that there is a difference between the group given snake fruit extract and the group not given snake fruit extract. Snake fruit extract contains phenolic and flavonoid metabolites that can lower triglyceride levels. Snake fruit extract can lower triglyceride levels in rats on a high-fat diet.

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Journal Info

Abbrev

pmj

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health

Description

Jurnal Farmasi Medika merupakan jurnal yang diterbitkan oleh PS. Farmasi FMIPA Universitas Sam Ratulangi dengan frekuensi terbit 2 kali dalam setahun di bulan Juni dan Desember. Tujuan pernebitan jurnal ini adalah untuk memberikan sarana bagi para akademisi, peneliti maupun praktisi untuk ...