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All Journal Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ
Jullianri Sari Lebang
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health

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EFEKTIVITAS EKSTRAK BUAH SALAK (Salacca zalacca) TERHADAP PROFIL TRIGLISERIDA TIKUS PUTIH DENGAN PENYAKIT HATI BERLEMAK NON ALKOHOL Olvie Syenni Datu; Jainer Pasca Siampa; Jullianri Sari Lebang
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol. 9 No. 1 (2026): Jurnal Farmasi Medika/Pharmacy Medical Journal
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pmj.v9i1.64675

Abstract

Hypertriglyceridemia is a condition of elevated triglyceride levels in the blood. High triglyceride levels in the blood can increase the risk of heart disease. High triglyceride levels are caused by consumption of high-fat foods, obesity, and metabolic syndrome. Snake fruit is a fruit rich in antioxidants and plays a role in degenerative diseases. Snake fruit potential to development as an alternative in treatment. This study aims to test the antihypertriglyceremic activity in rats induced by a high-fat diet using a mixture of quail eggs and used cooking oil, and then the rats were treated with 10%, 20%, and 40% snake fruit extract. The data obtained showed that the administration of snake fruit extract could reduce the triglyceride levels of rats induced by a high-fat diet back to normal levels of <150mg/dL compared to the group induced by a high-fat diet and not treated (negative control). These results show that there is a difference between the group given snake fruit extract and the group not given snake fruit extract. Snake fruit extract contains phenolic and flavonoid metabolites that can lower triglyceride levels. Snake fruit extract can lower triglyceride levels in rats on a high-fat diet.
Co-Authors Jainer Pasca Siampa Olvie Syenni Datu