<![CDATA[Background: Durian peel (Durio zibethinus Murr.), which is often discarded as agricultural waste, contains bioactive compounds such as flavonoids and tannins that exhibit antibacterial properties, particularly against acne-causing bacteria. Utilizing this waste material as a cosmetic ingredient could provide both environmental and economic benefits. Objective: This study aimed to evaluate the physical characteristics and stability of a serum formulation prepared with durian peel extract (Durio zibethinus Murr.) at a concentration of 15% Methods: The durian peel extract was obtained using the maceration method with 96% ethanol as the solvent and then formulated into a serum preparation. Physical quality evaluations included tests for color, homogeneity, pH, spreadability, adhesion, and viscosity. Stability testing was conducted through storage observation and the freeze–thaw method. Results: The Musang King variety produced the best formulation, characterized by a yellowish-brown color and homogeneous appearance. The pH remained stable between 4.67 and 6.65 before and after stability testing. Minor changes were observed in spreadability, adhesion, and viscosity values following freeze–thaw cycles, indicating good formulation stability. Irritation testing showed no significant adverse reactions among respondents. Conclusion: The durian peel extract–based serum demonstrated good physical quality and stable characteristics during storage, suggesting its potential use as a natural active ingredient in cosmetic formulations for acne-prone skin care.]]>
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