This study examined the influence of the principal's role, school climate, learning support, and entrepreneurship programs on the entrepreneurial interest of grade XII students at SMAN 2 Kepulauan Selayar. A quantitative ex post facto design was used with 141 students selected through proportional random sampling. Data were collected using Likert-scale questionnaires and analyzed using multiple linear regression with t-test, F-test, and coefficient of determination. The results showed that all predictors had positive and significant effects on entrepreneurial interest. The principal's role had a significant effect (t = 2.573; p = 0.011), school climate had a significant effect (t = 2.899; p = 0.004), learning support had a significant effect (t = 2.859; p = 0.005), and entrepreneurship programs had a significant effect (t = 2.574; p = 0.011). The simultaneous test was significant (F = 17.990; p < 0.001). The model explained 34.6% of the variance in entrepreneurial interest. These findings indicate that entrepreneurial interest is strengthened by integrated managerial, social, pedagogical, and programmatic support within the school ecosystem.
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