<![CDATA[Skin infections caused by this bacterium remain common, and antibiotic resistance continues to increase, creating a need for natural antibacterial sources. Andaliman leaves are one plant that can be used as a natural antibacterial active ingredient due to their content of flavonoids, tannins, saponins, terpenoids, and essential oils. This study aimed to determine whether n-hexane, ethyl acetate, and ethanol extracts of andaliman leaves exhibit antibacterial activity against Staphylococcus aureus. The study was conducted experimentally, beginning with successive extraction of andaliman leaves using n-hexane, ethyl acetate, and ethanol, followed by antibacterial activity testing using the disc diffusion method at concentrations of 20%, 30%, and 40%. The results showed that the n-hexane extract produced inhibition zones of 8.3±0.12 mm at 20%, 8.8±0.16 mm at 30%, and 9.3±0.04 mm at 40%. The ethyl acetate extract showed increased inhibitory activity with inhibition zones of 9.4 ± 0.28 mm at 20%, 12.7 ± 1.52 mm at 30%, and 16.0 ± 1.31 mm at 40%. The ethanol extract exhibited the highest antibacterial activity, with inhibition zones of 13.0±1.66 mm at 20%, 15.0±1.81 mm at 30%, and 19.4±1.12mmat40%.]]>
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