Learning becomes meaningful when it is carried out in a contextual manner. But, Biology education in Papua tends to follow national standards, as the textbooks used in schools are provided by the government which does not include elemnts of Papuan local wisdom. In addition, information technology is essential for developing 21st-century learning skills. This biology module based on Papuan local wisdom and integrated with IT can serve as an option in the learning process. This study aims to develop a biology module based on Papuan local wisdom that is integrated with IT. This study employs a research and development (R&D) methodology using the 4D (four-D) model, which includes the define, design, development, and disseminate stages. The developed product is a biology module containing material on biodiversity linked to Papuan local wisdom and supported by the integration of information technology in the form of educational images and videos accessible via QR codes. Product validity was assessed by two validators to evaluate content, language, and presentation. Meanwhile, the practicality and effectiveness test was conducted on 14 tenth-grade science students at Meepago State High School. The test results showed that the developed modules met the criteria for very validity, very practicality, very effective.
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