<![CDATA[This article critically examines Karl Raimund Popper's theory of falsification as one of the most significant epistemological contributions to the philosophy of science in the twentieth century. Despite extensive scholarship on Popperian philosophy, there remains a gap in the literature regarding its integrated methodological application, particularly in the context of contemporary scientific research and integrative Islamic scholarship. This study employs a qualitative library research approach, utilizing historical analysis, conceptual analysis, and critical synthesis as its analytical framework. Primary sources include Popper's foundational works, The Logic of Scientific Discovery (1959) and Conjectures and Refutations (1963), supplemented by relevant secondary and tertiary literature. The findings indicate that falsification emerged as a critical response to the Vienna Circle's verification principle, offering a more robust demarcation criterion that distinguishes empirical science from non-science based on a theory's falsifiability. Rather than serving merely as a logical procedure, falsification carries concrete methodological implications: a paradigmatic shift from inductive to hypothetico-deductive logic, the emergence of corroboration as a replacement for absolute confirmation, and a demand for critical rigor in hypothesis formulation. This article further argues that the epistemological limitations of falsification, including its susceptibility to auxiliary hypothesis manipulation as identified in the Duhem-Quine thesis, require engagement with post-Popperian frameworks such as Lakatos's research programmes. Ultimately, falsification remains an indispensable epistemological tool for maintaining methodological integrity in research that claims scientific status.]]>
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